Scottsdale-based regenerative medicine network with clinics in the US and Mexico
R3 Stem Cell is a Scottsdale, Arizona company that sells regenerative medicine treatments through a network of clinics. Dr. David Greene, a fellowship-trained orthopedic spine surgeon who moved to the business side of medicine, started it in 2012 while he was in business school at Arizona State, and he still runs it as CEO. R3's own pages put the network at 45 centers in seven countries in some places and 80 in eight countries in others, with more than 29,000 procedures reported since it began. R3 owns only a few of those clinics outright. The main one is a 7,000 square foot building on East Dynamite Boulevard in north Scottsdale that houses the stem cell center and R3's medspa arm, and there are R3 Anti Aging clinics in Beverly Hills and Brentwood, Tennessee. Everything else is an independent practice that joined R3's partnership program and uses its biologics, training, and marketing. The several hundred city pages on r3stemcell.com are search landing pages, not separate offices. What gets delivered depends on the country. In the US the visits are same-day outpatient injections: platelet-rich plasma, bone marrow or fat drawn from the patient, and donated umbilical cord or amniotic tissue allograft, placed under ultrasound guidance when the target calls for it. The intravenous protocols priced by cell count, from 25 million up to 250 million umbilical cord mesenchymal cells, are given at the Mexico clinics in Tijuana, Puerto Vallarta, and Cancun. None of it is FDA-approved. R3 registered a patient-funded observational study of amniotic and umbilical cord tissue on ClinicalTrials.gov in 2019 under NCT03899298, which is still listed there as not yet recruiting. Consultations are free, insurance does not pay, and published prices start at $3,999 in Mexico and $5,500 per joint in the US.
Starting from
$3,999
per treatment
Typical range
$3,999 โ $18,499
Prices are published rather than quoted privately. In the US, one extremity joint such as a knee with umbilical cord allograft starts around $5,500, and more involved cases run to about $15,000. At the Mexico clinics the protocols are priced by cell count, from $3,999 for 25 million cells to $18,499 for 250 million, with exosome-only IV protocols between $4,999 and $7,999. The first consultation is free and insurance does not cover any of it.
Pricing is indicative and set by each clinic. Confirm the final cost directly before treatment.
Individual results vary and are not typical or guaranteed. Case studies and testimonials reflect one person's experience.
Dr. David Greene
Founder and Chief Executive Officer
MD, PhD, MBA; fellowship-trained orthopedic spine surgeon
Trained in orthopedic surgery with a spine fellowship, then moved to the business side of medicine and started R3 in 2012 out of a project at Arizona State's business school. He sets the company's protocols and runs the partner network from Scottsdale, and no longer treats patients himself.
Dr. Sabrina Solt
Provider, R3 Scottsdale
NMD, naturopathic medical doctor
Does the injection work at the Scottsdale center, including ultrasound-guided musculoskeletal injections, PRP, adipose and bone marrow procedures, and birth-tissue biologics. She has practiced regenerative and anti-aging medicine in Arizona since 2013.
Dr. Francisco Fernandez
Medical Director, R3 Stem Cell Mexico
MD, Autonomous University of Baja California School of Medicine
Oversees the Mexico clinics, where the higher cell-count intravenous protocols are given. He worked in the IMSS hospital system before moving into regenerative medicine.
Not yet verified
This clinic has not completed verification. Listings are still curated, but accreditation hasn't been confirmed.
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40% Regenerative Orthopedics ยท 30% Bone-Marrow-Derived Therapy ยท 20% Platelet-Rich Plasma (PRP)
Pricing on consultation
70% Stem Cell Banking / Storage ยท 20% Bone-Marrow-Derived Therapy ยท 10% Adipose-Derived Stem Cell Therapy
Starting from
$3,000
30% IV / Systemic Cell Therapy ยท 25% Mesenchymal Stem Cell (MSC) Therapy ยท 15% Adipose-Derived Stem Cell Therapy
Starting from
$5,000